Yes. But it takes time and care. Like any other opioid, discontinuing Suboxone causes withdrawal. Suboxone stays in your system for a relatively long time, so withdrawal is not as fast or severe as with fentanyl, heroin, or oxycodone. Withdrawal symptoms are generally milder, but also longer lasting. Reducing your maintenance dose of buprenorphine has to be done slowly and it involves a number of risks.